Pharmaceutical Sciences

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Metabolism / Evaluation / Pharmacokinetics / Drug metabolism / Mitochondria / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

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Antitumor effect of adriamycin‐encapsulated nanoparticles of poly (DL‐lactide‐co‐glycolide)‐grafted dextran

Nanoparticles / Humans / Mice / Pharmaceutical Sciences / Animals / Doxorubicin / Particle Size / Freeze Drying / Drug Carriers / Lactic Acid / Cell Survival / Colorectal Neoplasms / Doxorubicin / Particle Size / Freeze Drying / Drug Carriers / Lactic Acid / Cell Survival / Colorectal Neoplasms

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Development of lamellar gel phase emulsion containing marigold oil (Calendula officinalis) as a potential modern wound dressing

Wound Healing / Pharmaceutical Sciences

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PHARMACOGNOSTIC EVALUATION AND PHARMACOLOGICAL PROPERTIES NELUMBO NUCIFERA SEED EXTRACT

Pharmacology / Clinical Biochemistry / Pharmaceutical Sciences

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Pharmacological Properties of Bauhinia Racemosa Lam

Pharmaceutical Sciences

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

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Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

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Development of lamellar gel phase emulsion containing marigold oil (Calendula officinalis) as a potential modern wound dressing

Water / Wound Healing / Apoptosis / Cell line / Collagen / Mice / Pharmaceutical Sciences / Animals / Male / Skin / Gels / Necrosis / Emulsions / Surface Active Agents / Wistar Rats / Bandages / Plant Oils / Calendula / Mice / Pharmaceutical Sciences / Animals / Male / Skin / Gels / Necrosis / Emulsions / Surface Active Agents / Wistar Rats / Bandages / Plant Oils / Calendula

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PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIMICROBIAL ACTIVITIES OF IN VITRO AND IN VIVO GROWN PLANT EXTRACTS OF LOBELIA INFLATA L

Biological Chemistry / Pharmaceutical Sciences / Pharmacy and Pharmaceutical Sciences

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Potential Ex-vivo Anti-inflammatory, Cardioprotective Properties and Phytochemical Properties of Leaves of Mussaenda Roxburghii Hook

Pharmacology / Pharmacy / Clinical Pharmacology / Pharmaceutical Marketing / Pharmacology and Clinical pharmacy / In Vitro and Vivo Pharmacology / Pharmaceutical Sciences / Cardiovascular Pharmacology / Opioid Pharmacology / Pharmacology and toxicology / Research on Anti Diabetic Plants / Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. / Brand Management (especially Pharmaceutical Branding and Retail Branding), Consumer Behaviour, Marketing Research / Medicinal Plant Pharmacology / In Vitro and Vivo Pharmacology / Pharmaceutical Sciences / Cardiovascular Pharmacology / Opioid Pharmacology / Pharmacology and toxicology / Research on Anti Diabetic Plants / Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. / Brand Management (especially Pharmaceutical Branding and Retail Branding), Consumer Behaviour, Marketing Research / Medicinal Plant Pharmacology

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R-[N-acetyl]eglin c:poly(oxyethylene) conjugates: Preparation, plasma persistence, and urinary excretion

Mice / Pharmaceutical Sciences / Animals / Male / Proteins / Amino Acid Sequence / Polyethylene Glycols / Amino Acid Sequence / Polyethylene Glycols

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Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Drug metabolism / Dogs / Cell line / Humans / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

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Transdermal iontophoretic drug delivery: Mechanistic analysis and application to polypeptide delivery

Chemistry / Drug delivery / Insulin / Mice / Pharmaceutical Sciences / Animals / Peptides / Iontophoresis / Electrolytes / Buffers / Electrodes / Animals / Peptides / Iontophoresis / Electrolytes / Buffers / Electrodes

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Stereochemical preferences for curarimimetic neuromuscular junction blockade II: Enantiomeric bisquaternary amines as probes

Chemistry / Animal Behavior / Kinetics / Cats / Amines / Mice / Blood Pressure / Pharmaceutical Sciences / Animals / Male / Acetylcholine / Cholinesterase inhibitors / Tongue / Molecular Conformation / Hypoglossal Nerve / Erythrocytes / Protein Binding / Blood Proteins / Mice / Blood Pressure / Pharmaceutical Sciences / Animals / Male / Acetylcholine / Cholinesterase inhibitors / Tongue / Molecular Conformation / Hypoglossal Nerve / Erythrocytes / Protein Binding / Blood Proteins

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